π¬ Latest pharma industry updates π
π€ Merck is acquiring Terns Pharmaceuticals for about $6.7B, adding TERN-701 in Phase 1/2 for chronic myeloid leukemia, as it prepares for future Keytruda patent loss.
π° Earendil Labs raised $787M to scale an AI-driven pipeline of biologics for autoimmune diseases and cancer, backed by investors including Sanofi.
π€ Gilead Sciences will buy Ouro Medicines for up to about $2.2B to strengthen immunology, gaining OM336, a BCMAxCD3 T-cell engager in early trials for severe autoimmune diseases like AIHA and ITP.
β Corcept Therapeutics won FDA approval for Lifyorli with nab-paclitaxel in platinum-resistant ovarian cancer, marking the 1st approved selective glucocorticoid receptor antagonist.
βοΈ Novo Nordisk sued in India to stop Dr. Reddyβs Laboratoriesβs from selling generic semaglutide as βOlymviq,β arguing the name is too close to Ozempic.
π’ Recordati confirmed possible takeover discussions with CVC Capital Partners, with a reported offer that could value the Italian drugmaker at roughly β¬11B.
π€ Otsuka Pharmaceutical Co., Ltd. will acquire Transcend Therapeutics for up to $1.3B, to gain an experimental psychiatric medicine being explored for PTSD and other mental health disorders.
π China pledged fairer trade and more openness to foreign companies, including in pharma, promising stronger IP protection, clearer policies, and equal treatment for international drugmakers.
π€ Novartis will acquire Excellergy in a deal worth up to $2B to gain Exl-111, an experimental allergy therapy targeting IgE that could improve on widely used medicine Xolair.
π¦ Valneva and Pfizer reported positive Phase 3 Lyme vaccine data, but markets reacted cautiously because the trial narrowly missed the prespecified statistical threshold.
πΆ Abivax ended 2025 with β¬530.4M in cash, funding operations into Q4 2027, while confirming no new safety signal in Phase 3 ulcerative colitis testing of obefazimod ahead of key data due by end-Q2 2026.
π¬ Sanofi licensed Kali Therapeuticsβs Phase 1 trispecific T-cell engager KT501 for autoimmune diseases for up to $1.2B total.
π€ Merck also partnered with Quotient Therapeutics, paying up to $2.2B total, to use somatic genomics to discover new inflammatory bowel disease drug targets.
π° Shionogi & Co., Ltd will pay $100M upfront to buy Apnimedβs 50% stake in their sleep-disorder joint venture.
π¦ RA Capital filed a $50M SPAC aimed at merging with a China-based biotech or healthcare company, betting both on a SPAC comeback and Chinaβs continued strength in clinical-stage biotech assets.
π§ FDA granted accelerated approval to Denali Therapeuticsβs Avlayah for Hunter syndrome, the 1st biologic designed to reach the brain and treat neurological symptoms.

